Ways to attain super power 
Super Mario : Mushrooms
Popeye : Spinach
Hulk   : Anger
T cells :      ???

The fascination towards the whole adaptive nature of the immune response and its ability to orchestrate a specific response to a particular infection is the major reason for pursuing the current line of research. In particular, our immune system has been armed with only a limited number of immune cells and still it has been capable of generating appropriate response to control the immediate infection and protect the hosts from future infection.

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An infection triggers a wide variety of immune cells to the site of infection, mainly the innate immune cells during the early phase of infection. These cells secrete a variety of proteins called cytokines and chemokines to alert and recruit the adaptive immune cells to the site of infection where they get programmed to provide a specific targeted immune response. Eventually, most of these adaptive immune cells undergo apototic cell death while some remain in the host to protect from future infections. After decades of research, we still do not know completely about activation and differentiation of T cells. While the advent of Next Generation Sequencing Technologies has led to unraveling of interesting details, it has also raised more questions about how the entire differentiation process works. Currently we are investigating about 1) the cytokines and 2) evlutionarily conserved signaling pathways involved in the differentiation process.